Top 10 Biggest Losers of Season 2010 — Before and After

01. Patrick House

Starting weight: 400 lbs.
Finale weight: 219 lbs.
Lost 181 lbs., 45.25 percent

The 28-year-old sales rep from Vicksburg, Miss., won “The Biggest Loser” and took home the $250,000 prize.  This season’s “Biggest Loser” and winner of the $250,000 grand prize, Patrick,